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CT images and tracings of cardiac rate (in beats per minute) and respiratory rate (in breaths per minute) during percutaneous radio-frequency treatment of an osteoid osteoma after establishment of general anesthesia. Times A, B, and C marked on the tracings correspond to the needle positions shown on CT images A-C, respectively. Notice that (A) soft-tissue penetration and (B) drilling through periosteum and cortical bone elicit no response, but (C) puncture of the tumor causes a sudden marked increase in cardiac and respiratory rates. H = hour, MIN = minutes.
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