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Renal Cyst Ablation with n-Butyl Cyanoacrylate and Iodized Oil in Symptomatic Patients with Autosomal Dominant Polycystic Kidney Disease: Preliminary Report¹

¹ From the Departments of Radiology (Seung Hyup Kim, M.W.M., H.J.L., J.S.S., Sun Ho Kim) and Internal Medicine (C.A.), Seoul National University Hospital, 28 Yongon-Dong, Chongno-Gu, Seoul 110-744, Korea; Institute of Radiation Medicine, Seoul National University Medical Research Center, Korea; and Clinical Research Institute, Seoul National University Hospital, Korea. Received September 24, 2001; revision requested October 29; final revision received May 6, 2002; accepted May 7. Supported by Seoul National University Research Fund 2001. Address correspondence to Seung Hyup Kim (e-mail: kimsh@radcom.snu.ac.kr).

View larger version (116K): [in a new window]   Figure a.ADPKD in a 37-year-old man. (a-c) Transverse contrast-enhanced CT scans from cranial to caudal levels show multiple cysts in both kidneys. Cyst ablation was performed in two cysts (1,2) in the right kidney and in two cysts (3,4) in the left kidney. (d) Posteroanterior radiograph obtained after the procedure shows opacities that represent the mixture of NBCA and iodized oil in the treated right cysts (1,2). (e) Posteroanterior radiograph obtained after the procedure shows opacities that represent the mixture of NBCA and iodized oil in the treated left cysts. (f-h) Follow-up transverse nonenhanced CT scans from cranial to caudal levels obtained 11 months after the procedure show shrunken cysts (1-4) filled with the mixture of NBCA and iodized oil.

View larger version (116K): [in a new window]   Figure b.ADPKD in a 37-year-old man. (a-c) Transverse contrast-enhanced CT scans from cranial to caudal levels show multiple cysts in both kidneys. Cyst ablation was performed in two cysts (1,2) in the right kidney and in two cysts (3,4) in the left kidney. (d) Posteroanterior radiograph obtained after the procedure shows opacities that represent the mixture of NBCA and iodized oil in the treated right cysts (1,2). (e) Posteroanterior radiograph obtained after the procedure shows opacities that represent the mixture of NBCA and iodized oil in the treated left cysts. (f-h) Follow-up transverse nonenhanced CT scans from cranial to caudal levels obtained 11 months after the procedure show shrunken cysts (1-4) filled with the mixture of NBCA and iodized oil.

View larger version (109K): [in a new window]   Figure c.ADPKD in a 37-year-old man. (a-c) Transverse contrast-enhanced CT scans from cranial to caudal levels show multiple cysts in both kidneys. Cyst ablation was performed in two cysts (1,2) in the right kidney and in two cysts (3,4) in the left kidney. (d) Posteroanterior radiograph obtained after the procedure shows opacities that represent the mixture of NBCA and iodized oil in the treated right cysts (1,2). (e) Posteroanterior radiograph obtained after the procedure shows opacities that represent the mixture of NBCA and iodized oil in the treated left cysts. (f-h) Follow-up transverse nonenhanced CT scans from cranial to caudal levels obtained 11 months after the procedure show shrunken cysts (1-4) filled with the mixture of NBCA and iodized oil.

View larger version (168K): [in a new window]   Figure d.ADPKD in a 37-year-old man. (a-c) Transverse contrast-enhanced CT scans from cranial to caudal levels show multiple cysts in both kidneys. Cyst ablation was performed in two cysts (1,2) in the right kidney and in two cysts (3,4) in the left kidney. (d) Posteroanterior radiograph obtained after the procedure shows opacities that represent the mixture of NBCA and iodized oil in the treated right cysts (1,2). (e) Posteroanterior radiograph obtained after the procedure shows opacities that represent the mixture of NBCA and iodized oil in the treated left cysts. (f-h) Follow-up transverse nonenhanced CT scans from cranial to caudal levels obtained 11 months after the procedure show shrunken cysts (1-4) filled with the mixture of NBCA and iodized oil.

View larger version (144K): [in a new window]   Figure e.ADPKD in a 37-year-old man. (a-c) Transverse contrast-enhanced CT scans from cranial to caudal levels show multiple cysts in both kidneys. Cyst ablation was performed in two cysts (1,2) in the right kidney and in two cysts (3,4) in the left kidney. (d) Posteroanterior radiograph obtained after the procedure shows opacities that represent the mixture of NBCA and iodized oil in the treated right cysts (1,2). (e) Posteroanterior radiograph obtained after the procedure shows opacities that represent the mixture of NBCA and iodized oil in the treated left cysts. (f-h) Follow-up transverse nonenhanced CT scans from cranial to caudal levels obtained 11 months after the procedure show shrunken cysts (1-4) filled with the mixture of NBCA and iodized oil.

View larger version (112K): [in a new window]   Figure f.ADPKD in a 37-year-old man. (a-c) Transverse contrast-enhanced CT scans from cranial to caudal levels show multiple cysts in both kidneys. Cyst ablation was performed in two cysts (1,2) in the right kidney and in two cysts (3,4) in the left kidney. (d) Posteroanterior radiograph obtained after the procedure shows opacities that represent the mixture of NBCA and iodized oil in the treated right cysts (1,2). (e) Posteroanterior radiograph obtained after the procedure shows opacities that represent the mixture of NBCA and iodized oil in the treated left cysts. (f-h) Follow-up transverse nonenhanced CT scans from cranial to caudal levels obtained 11 months after the procedure show shrunken cysts (1-4) filled with the mixture of NBCA and iodized oil.

View larger version (112K): [in a new window]   Figure g.ADPKD in a 37-year-old man. (a-c) Transverse contrast-enhanced CT scans from cranial to caudal levels show multiple cysts in both kidneys. Cyst ablation was performed in two cysts (1,2) in the right kidney and in two cysts (3,4) in the left kidney. (d) Posteroanterior radiograph obtained after the procedure shows opacities that represent the mixture of NBCA and iodized oil in the treated right cysts (1,2). (e) Posteroanterior radiograph obtained after the procedure shows opacities that represent the mixture of NBCA and iodized oil in the treated left cysts. (f-h) Follow-up transverse nonenhanced CT scans from cranial to caudal levels obtained 11 months after the procedure show shrunken cysts (1-4) filled with the mixture of NBCA and iodized oil.

View larger version (105K): [in a new window]   Figure h.ADPKD in a 37-year-old man. (a-c) Transverse contrast-enhanced CT scans from cranial to caudal levels show multiple cysts in both kidneys. Cyst ablation was performed in two cysts (1,2) in the right kidney and in two cysts (3,4) in the left kidney. (d) Posteroanterior radiograph obtained after the procedure shows opacities that represent the mixture of NBCA and iodized oil in the treated right cysts (1,2). (e) Posteroanterior radiograph obtained after the procedure shows opacities that represent the mixture of NBCA and iodized oil in the treated left cysts. (f-h) Follow-up transverse nonenhanced CT scans from cranial to caudal levels obtained 11 months after the procedure show shrunken cysts (1-4) filled with the mixture of NBCA and iodized oil.