Published online before print April 24, 2003, 10.1148/radiol.2273020535
Myelomeningocele: Prenatal Evaluation—Comparison between Transabdominal US and MR Imaging1
Oran S. Aaronson, MD,
Marta Hernanz-Schulman, MD,
Joseph P. Bruner, MD,
George W. Reed, PhD and
Noel B. Tulipan, MD
1 From the Departments of Neurosurgery (O.S.A., N.B.T.), Radiology (M.H.S.), and Obstetrics and Gynecology (J.P.B.), Vanderbilt University Medical Center, A-2219 Medical Center North, Nashville, TN 37232; and Division of Preventive and Behavioral Medicine, University of Massachusetts Medical School, Worcester (G.W.R.). Received May 6, 2002; revision requested June 21; final revision received September 27; accepted October 25. Supported by a grant from the Dana Foundation. Address correspondence to N.B.T. (e-mail: noel.tulipan@vanderbilt.edu).

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Figure 1. Prenatal transabdominal US images of a fetus at an estimated gestational age of 22 weeks. The spine is seen in the transverse plane. Left: Image shows intact laminae at the level of the distal abdominal aorta (arrow). Center: Image demonstrates the beginning of posterior element separation (curved arrows) and the myelomeningocele sac (straight arrow), below the aortic bifurcation. Right: Image shows wide-open posterior elements (curved arrows) and the myelomeningocele sac (straight arrow) at the level of the iliac crests at L5. Therefore, the most cephalic level of the dysraphic defect is at L4, as seen in the center image.
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Figure 2. Prenatal sagittal fast spin-echo MR image (1,200/120 [repetition time msec/echo time msec]) obtained in a fetus at an estimated gestational age of 24 weeks. The dysraphic defect (arrow) begins at L3.
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Figure 3. Postnatal sagittal T2-weighted MR image (3,600/113) in the newborn who is depicted prenatally in Figure 2 demonstrates the dysraphic defect (arrow) beginning at L4. The tethered neural placode is seen one level below, at L5. Image quality of this image was better than that of the T1-weighted image (not shown).
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Figure 4. Postnatal anteroposterior spinal radiograph of the same patient as in Figures 2 and 3 demonstrates spinal dysraphia beginning at L4. Note the laminar separation (arrows) at this level.
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Copyright © 2003 by the Radiological Society of North America.