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Quantification of Coronary Artery Calcium with Multi–Detector row CT: Assessing Interscan Variability with Different Tube Currents—Pilot Study¹

¹ From the Mallinckrodt Institute of Radiology, Washington University, School of Medicine, 510 S Kingshighway Blvd, St Louis, MO 63110. From the 2001 RSNA Scientific Assembly. Received December 13, 2001; revision requested February 18, 2002; final revision received October 30; accepted November 11. Address correspondence to K.T.B. (e-mail: baet@mir.wustl.edu).

View larger version (181K): [in a new window]   Figure 1. A and B, Two consecutive transverse CT scans obtained with (A) 150 mAs and (B) 40 mAs in one subject. C and D, Two consecutive transverse CT scans obtained with (C) 150 mAs and (D) 80 mAs in another subject. All four scans show calcium deposits (arrows in A and C) in the left anterior descending artery. Increases in noise with lower dose values are apparent in these images.

View larger version (29K): [in a new window]   Figure 2. The log-transformed calcium scores of low-dose scans and high-dose scans according to vessel are highly correlated (r = 0.98). = left main coronary artery, = left anterior descending coronary artery, = circumflex coronary artery, x = right coronary artery. In this logarithm calcium score scale, 0-1, 1-2, and 2-3 ranges correspond to minimal-, moderate-, and high-risk categories, respectively.

View larger version (27K): [in a new window]   Figure 3. The absolute percentage differences for calcium score by vessel between the subject group that underwent 40-mAs and 150-mAs examinations () versus the subject group that underwent 80-mAs and 150-mAs examinations (). There was no significant difference between the two groups with respect to total score of the subject (independent samples t test, P = .25) or the vessel (independent samples t test, P = .84).