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Published online before print May 20, 2003, 10.1148/radiol.2281020718
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Small Hepatocellular Carcinoma in Cirrhosis: Randomized Comparison of Radio-frequency Thermal Ablation versus Percutaneous Ethanol Injection1

Riccardo A. Lencioni, MD, Hans-Peter Allgaier, MD, Dania Cioni, MD, Manfred Olschewski, MSc, Peter Deibert, MD, Laura Crocetti, MD, Holger Frings, MD, Joerg Laubenberger, MD, Ina Zuber, MD, Hubert E. Blum, MD and Carlo Bartolozzi, MD

1 From the Division of Diagnostic and Interventional Radiology, Department of Oncology, Transplants and Advanced Technologies in Medicine, University of Pisa, Via Roma 67, I-56125 Pisa, Italy (R.A.L., D.C., L.C., C.B.); and the Departments of Medicine II (H.P.A., P.D., H.F., I.Z., H.E.B.), Medical Biometry (M.O.), and Radiology (J.L.), University Hospital Freiburg, Germany. From the 2001 RSNA scientific assembly. Received June 17, 2002; revision requested August 8; final revision received November 26; accepted December 19. Address correspondence to R.A.L. (e-mail: lencioni@do.med.unipi.it).



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  		Figure 1. Graph shows the probability of local recurrence-free survival in patients with HCC treated with PEI (n = 50) or RF thermal ablation (RFTA, n = 52). The difference between the groups was statistically significant (P = .002). The number of patients followed up at 6, 12, 18, 24, and 30 months was 46, 37, 24, 16, and five, respectively, for the PEI group and 49, 46, 33, 24, and 10, respectively, for the RF group.

 


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  		Figure 2. Graph shows the probability of event-free survival in patients with HCC treated with PEI (n = 50) or RF thermal ablation (RFTA, n = 52). The difference between the groups was statistically significant (P = .012). The number of patients followed up at 6, 12, 18, 24, and 30 months was 45, 34, 21, 12, and two, respectively, for the PEI group and 49, 42, 30, 20, and eight, respectively, for the RF group.

 




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