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Cardiovascular Effects at Multi–Detector Row CT Colonography Compared with Those at Conventional Endoscopy of the Colon¹

¹ From the Department of Intestinal Imaging (S.A.T., S.H., S.M., P.B., C.I.B.), Wolfson Institute of Endoscopy (B.P.S., M.V., A.W.), Department of Cardiology (C.O., H.M., Y.S., H.B.), and Cancer Research UK Colorectal Cancer Unit (S.H., W.A.), St. Mark’s Hospital, Level 4V, Watford Road, Northwick Park, London HA1 3UJ, England, United Kingdom. Received November 22, 2002; revision requested January 22, 2003; final revision received April 19; accepted May 5. Supported by grants from the Radiological Research Trust and the Wexham Gastrointestinal Trust. S.A.T. supported by a grant from the Royal College of Radiologists. Address correspondence to S.H. (e-mail: s.halligan@imperial.ac.uk).

View larger version (21K): [in a new window]   Figure 1. Bar graph illustrates changes defined as clinically important that occurred in 104 patients during or after CT colonography (white bars) and during or after colonoscopy (black bars). No patients developed hypotension or hypoxia during or after CT colonography, unlike at colonoscopy. sats = oxygen saturation.

View larger version (21K): [in a new window]   Figure 2. Bar graph illustrates changes defined as clinically important that occurred in 40 patients during or after CT colonography (white bars) and during or after flexible sigmoidoscopy (black bars). A significantly greater number of patients developed tachycardia at CT, whereas a significantly greater number of patients developed bradycardia at sigmoidoscopy. sats = oxygen saturation.

View larger version (20K): [in a new window]   Figure 3. Bar graph depicts the peri-CT colonography (white bars) and periendoscopy (ie, both colonoscopy and sigmoidoscopy) (black bars) incidence of supraventricular arrhythmia in 33 patients. There was no significant difference in incidence of any type of supraventicular arrythmia between the two procedures.

View larger version (21K): [in a new window]   Figure 4. Bar graph depicts the peri-CT colonography (white bars) and periendoscopy (ie, both colonoscopy and sigmoidoscopy) (black bars) incidence of ventricular arrhythmia in 33 patients. Overall, there was no significant difference in incidence of any type of ventricular arrhythmia between the two procedures, although patients with a history of cardiac disease were at significantly greater risk of experiencing ventricular couplets at periendoscopy than at peri-CT colonography (P = .002).