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Published online before print April 2, 2004, 10.1148/radiol.2312021393
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Pulmonary Disease Assessment in Cystic Fibrosis: Comparison of CT Scoring Systems and Value of Bronchial and Arterial Dimension Measurements1

Pim A. de Jong, MSc, Mark D. Ottink, MD, Simon G. F. Robben, MD, PhD, Maarten H. Lequin, MD, PhD, Wim C. J. Hop, PhD, Johan J. E. Hendriks, MD, PhD, Peter D. Paré, MD and Harm A. W. M. Tiddens, MD, PhD

1 From the Depts of Paediatric Pulmonology (P.A.d.J., H.A.W.M.T.) and Paediatric Radiology (M.H.L.), Erasmus Med Ctr Rotterdam, Sophia Children’s Hosp, Dr Molewaterplein 60, 3015 GJ Rotterdam, the Netherlands; Dept of Epidemiology and Biostatistics (W.C.J.H.), Erasmus Med Ctr Rotterdam, the Netherlands; Depts of Paediatric Pulmonology (M.D.O., J.J.E.H.) and Radiology (S.G.F.R.), Univ Hosp Maastricht, the Netherlands; and Univ of British Columbia, McDonald Research Lab and iCAPTURE Ctr, St Paul’s Hosp, Vancouver, Canada (P.D.P.). Received Oct 29, 2002; revision requested Jan 9, 2003; final revision received Sep 10; accepted Sep 29. Address correspondence to H.A.W.M.T. (e-mail: h.tiddens@erasmusmc.nl).



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  		Figure 1. Graph shows relationship between Bhalla score and FEV1 value (R = –0.73, P < .01).

 


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  		Figure 2. Abnormal transverse thin-section CT scans obtained in a 13-year-old boy with normal PFT results as follows: FEV1, 99 percentage predicted; FVC, 92 percentage predicted; FEV1/FVC ratio, 90%; and FEF25%-75%, 95 percentage predicted. Thin-section CT scores were as follows: Castile score, 22 (range, 0-92); Brody score, 17 (range, 0-100); Helbich score, 12 (range, 0-27); Santamaria score, 13 (range, 0-29); Bhalla score, 12 (range, 0-25). Left: Scan shows bronchiectasis with a diameter of the artery that was two to three times that of the artery at an intermediate location (1). Center: Scan shows cysts in the periphery of the lung (2), bronchiectasis with a diameter of the artery that was one to two times that of the artery at a central location (3), and mucus-plugged bronchus (4). Right: Scan shows cysts in the periphery of the lung (5).

 




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