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DOI: 10.1148/radiol.2312030553
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Small Pulmonary Nodules: Reproducibility of Three-dimensional Volumetric Measurement and Estimation of Time to Follow-up CT1

William J. Kostis, PhD, David F. Yankelevitz, MD, Anthony P. Reeves, PhD, Simina C. Fluture, MS and Claudia I. Henschke, PhD, MD

1 From the Department of Radiology, Weill Medical College of Cornell University, 525 E 68th St, New York, NY 10021 (W.J.K., D.F.Y., S.C.F., C.I.H.); and School of Electrical and Computer Engineering, Cornell University, Ithaca, NY (A.P.R.). Received April 8, 2003; revision requested June 20; revision received August 17; accepted September 29. Supported in part by National Institutes of Health grant R01-CA78905. Address correspondence to C.I.H. (e-mail: chensch@med.cornell.edu).



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  		Figure 1. Images of two nodules with patient-induced artifacts. Left: Two-dimensional transverse CT scans. Right: Surface-shaded renderings. Top: Images show patient motion, with dramatic effect on volumetric analysis. Bottom: Images show cardiac motion, with a more subtle effect on volumetric analysis.

 


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  		Figure 2. Images of 8-mm stable pulmonary nodule. Top: Two-dimensional transverse CT scan. Bottom left: Three-dimensional surface-shaded rendering at initial CT. Bottom right: Rendering at follow-up CT 181 days later. Surface-shaded representations illustrate both that the attached vessel has been removed from the nodule and that the nodule volume has not changed appreciably between acquisition of scans.

 




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