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DOI: 10.1148/radiol.2313031088
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Effect of Smoking on Restenosis during the 1st Year after Lower-Limb Endovascular Interventions1

Martin Schillinger, MD, Markus Exner, MD, Wolfgang Mlekusch, MD, Markus Haumer, MD, Schila Sabeti, MD, Ramazanali Ahmadi, MD, Oswald Wagner, MD and Erich Minar, MD

1 From the Departments of Angiology (M.S., W.M., M.H., S.S., R.A., E.M.) and Laboratory Medicine (M.E., O.W.), University of Vienna, Medical School, Waehringer Guertel 18–20, A-1090 Vienna, Austria. Received July 10, 2003; revision requested September 29; revision received October 1; accepted November 6. Address correspondence to M.S. (e-mail: martin.schillinger@akh-wien.ac.at).



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  		Figure 1. Graph shows cumulative freedom from restenosis at 24 hours and at 3, 6, 9, and 12 months after lower-limb endovascular treatment in 650 patients grouped according to smoking habits. Reduced rates of restenosis were observed at follow-up examinations in habitual smokers and heavy smokers (of whom 82 and 182, 78 and 153, 57 and 119, 44 and 93, and 36 and 73, respectively, were free from restenosis in the treated vascular segment at the five follow-up time-points) compared with nonsmokers and light smokers (of whom 352 and 54, 300 and 41, 224 and 33, 162 and 29, and 124 and 25, respectively, were free from restenosis in the treated segment at follow-up).

 


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  		Figure 2. Graphs show cumulative freedom from restenosis at 24 hours and at 3, 6, 9, and 12 months after endovascular treatment of iliac artery (left) (n = 178) or femoropopliteal artery (right) (n = 472) stenosis in habitual smokers and heavy smokers (>=10 cigarettes daily; continuous line) versus nonsmokers and light smokers (<10 cigarettes daily; dashed line). Reduced postintervention restenosis rates were observed for habitual smokers and heavy smokers, compared with those for nonsmokers and light smokers.

 




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