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Published online before print April 2, 2004, 10.1148/radiol.2312030421

(Radiology 2004;231:546.)

A more recent version of this article appeared on May 1, 2004
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De Novo Femoropopliteal Stenoses: Endovascular Gamma Irradiation Following Angioplasty—Angiographic and Clinical Follow-up in a Prospective Randomized Controlled Trial1

Karsten Krueger, MD, Markus Zaehringer, MD, Mark Bendel, MD, Hartmut Stuetzer, MD, David Strohe, Monika Nolte, PhD, Daniele Wittig, MD, Rolf-Peter Mueller, MD and Klaus Lackner, MD

1 From the Depts of Radiology (K.K., M.Z., D.S., D.W., K.L.) and Radiooncology (M.B., M.N., R.P.M.), and the Institute for Med Statistics, Informatics and Epidemiology (H.S.), Univ of Cologne, Joseph-Stelzmann-Str, D-50924 Cologne, Germany. From the 2001 RSNA scientific assembly. Received Mar 19, 2003; revision requested May 7; final revision received Aug 6; accepted Sep 16. Supported by a grant from "Cologne Fortune," a research program of the Univ of Cologne, Nr. 1/98. Address correspondence to K.K. (e-mail: karsten.krueger@uni-koeln.de).



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  		Figure 1a. (a) Graph illustrates peak velocity ratios at color duplex US. Mean peak velocity ratio (ratio of maximum blood velocity before stenosis to maximum blood velocity within stenosis) values for the irradiation ({blacksquare}) and control ({bullet}) groups before and shortly after PTA and at follow-up of up to 24 months are plotted. Results were significantly different between the two groups 3-12 months after PTA. (b) Graph illustrates ankle-brachial indexes at color duplex US. The mean ankle-brachial index was better in the irradiation group ({blacksquare}), but deteriorating values were observed in this group the second year after PTA. {bullet} = control group.

 


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  		Figure 1b. (a) Graph illustrates peak velocity ratios at color duplex US. Mean peak velocity ratio (ratio of maximum blood velocity before stenosis to maximum blood velocity within stenosis) values for the irradiation ({blacksquare}) and control ({bullet}) groups before and shortly after PTA and at follow-up of up to 24 months are plotted. Results were significantly different between the two groups 3-12 months after PTA. (b) Graph illustrates ankle-brachial indexes at color duplex US. The mean ankle-brachial index was better in the irradiation group ({blacksquare}), but deteriorating values were observed in this group the second year after PTA. {bullet} = control group.

 


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  		Figure 2a. Treadmill test results. (a) Mean results for treadmill walking distance capability with initial claudication (in meters) were favorable in the irradiation group ({blacksquare}) beginning 6 months after PTA. Differences were not significant between the irradiation and control ({bullet}) groups. (b) Mean results for treadmill walking distance capability with final claudication (in meters) were better in the irradiation group ({blacksquare}) up to 2 years after PTA. Differences were not significant between the two groups. {bullet} = control group.

 


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  		Figure 2b. Treadmill test results. (a) Mean results for treadmill walking distance capability with initial claudication (in meters) were favorable in the irradiation group ({blacksquare}) beginning 6 months after PTA. Differences were not significant between the irradiation and control ({bullet}) groups. (b) Mean results for treadmill walking distance capability with final claudication (in meters) were better in the irradiation group ({blacksquare}) up to 2 years after PTA. Differences were not significant between the two groups. {bullet} = control group.

 


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  		Figure 3. Structured interview results. The irradiation group ({blacksquare}) had more favorable results. A significant difference in interview points between the irradiation and control ({bullet}) groups was seen only at 12-month follow-up.

 




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