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DOI: 10.1148/radiol.2323032035
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Lung Image Database Consortium: Developing a Resource for the Medical Imaging Research Community1

Samuel G. Armato III, PhD, Geoffrey McLennan, MD, PhD, Michael F. McNitt-Gray, PhD, Charles R. Meyer, PhD, David Yankelevitz, MD, Denise R. Aberle, MD, Claudia I. Henschke, MD, PhD, Eric A. Hoffman, PhD, Ella A. Kazerooni, MD, MS, Heber MacMahon, MD, Anthony P. Reeves, PhD, Barbara Y. Croft, PhD and Laurence P. Clarke, PhD, For the Lung Image Database Consortium Research Group

1 From the Department of Radiology, MC 2026, University of Chicago, 5841 S Maryland Ave, Chicago, IL 60637 (S.G.A.). Affiliations for all other authors and the members of the Lung Image Database Consortium Research Group are listed at the end of this article. Received December 17, 2003; revision requested February 16, 2004; revision received March 11; accepted March 16. Supported in part by USPHS Grants U01CA091085, U01CA091090, U01CA091099, U01CA091100, and U01CA091103. Address correspondence to S.G.A. (e-mail: s-armato@uchicago.edu).



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  		Figure 1. Transverse thoracic CT scan shows a lesion (arrow) that clearly satisfies the Fleischner Society definition of a nodule.

 


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  		Figure 2. Transverse CT scan shows a lesion (arrow) that appears to satisfy the Fleischner Society definition of a nodule.

 


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  		Figure 3. The lesion shown in Figure 2 is shown in all transverse sections in which it appears on the CT scan. The irregular shape of the three-dimensional lesion is apparent. The region shown with a black border was extracted from the section shown in Figure 2.

 


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  		Figure 4. The term "nodule" refers to a spectrum of abnormalities that is itself part of a larger spectrum of abnormalities termed "focal abnormalities." This scar (far left) is a focal abnormality that would not be considered a nodule, as is the nonspecific opacity (far right), which is likely due to previous infection. The spiculated lesion (left-center) and the compact lesion (right-center) are two representative examples of lesions within the nodule spectrum. All images were obtained from transverse CT examinations.

 


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  		Figure 5. Lung nodule shown with outlines constructed by two radiologists independently. One radiologist constructed an outline that captured the core solid component of the nodule (black outline), while another radiologist constructed a less conservative outline that encompassed the nonsolid component, as well (white outline).

 




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