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CT of Deep Venous Thrombosis and Pulmonary Embolus: Does Iso-osmolar Contrast Agent Improve Vascular Opacification?¹

¹ From the Department of Radiology, Medical College of Wisconsin, 9200 W Wisconsin Ave, Milwaukee, WI 53226-3596. Received November 21, 2003; revision requested February 6, 2004; revision received May 6; accepted June 2. Supported by a grant from the Amersham Corporation, Princeton, NJ. Address correspondence to L.R.G. (e-mail: lgoodman@mcw.edu).

View larger version (107K): [in a new window]   Figure 1a. Comparison of attenuation of the interlobar pulmonary artery and the left common femoral vein on transverse CT scans obtained in (a) the index case (iodixanol), (b) the control case (iohexol), and (c) the index patient 18 months before a (iohexol). (a) Interlobar pulmonary artery attenuation was 230 HU. Left common femoral vein attenuation was 88 HU. (b) Interlobar pulmonary artery attenuation was 282 HU. Left common femoral vein attenuation was 80 HU. (c) Interlobar pulmonary artery attenuation was 173 HU. Left common femoral vein attenuation was 83 HU.

View larger version (99K): [in a new window]   Figure 1b. Comparison of attenuation of the interlobar pulmonary artery and the left common femoral vein on transverse CT scans obtained in (a) the index case (iodixanol), (b) the control case (iohexol), and (c) the index patient 18 months before a (iohexol). (a) Interlobar pulmonary artery attenuation was 230 HU. Left common femoral vein attenuation was 88 HU. (b) Interlobar pulmonary artery attenuation was 282 HU. Left common femoral vein attenuation was 80 HU. (c) Interlobar pulmonary artery attenuation was 173 HU. Left common femoral vein attenuation was 83 HU.

View larger version (107K): [in a new window]   Figure 1c. Comparison of attenuation of the interlobar pulmonary artery and the left common femoral vein on transverse CT scans obtained in (a) the index case (iodixanol), (b) the control case (iohexol), and (c) the index patient 18 months before a (iohexol). (a) Interlobar pulmonary artery attenuation was 230 HU. Left common femoral vein attenuation was 88 HU. (b) Interlobar pulmonary artery attenuation was 282 HU. Left common femoral vein attenuation was 80 HU. (c) Interlobar pulmonary artery attenuation was 173 HU. Left common femoral vein attenuation was 83 HU.

View larger version (25K): [in a new window]   Figure 2a. Graphs show venous attenuation correlation with weight for examinations with (a) iodixanol and (b) iohexol.

View larger version (24K): [in a new window]   Figure 2b. Graphs show venous attenuation correlation with weight for examinations with (a) iodixanol and (b) iohexol.

View larger version (23K): [in a new window]   Figure 3a. Graphs show arterial attenuation correlation with weight for examinations with (a) iodixanol and (b) iohexol.

View larger version (24K): [in a new window]   Figure 3b. Graphs show arterial attenuation correlation with weight for examinations with (a) iodixanol and (b) iohexol.