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Published online before print February 28, 2007, 10.1148/radiol.2431060069
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Hypervascular Hepatocellular Carcinomas: Bolus Tracking with a 40-Detector CT Scanner to Time Arterial Phase Imaging1

Shamima Sultana, MD, Kazuo Awai, MD, Yoshiharu Nakayama, MD, Takeshi Nakaura, MD, Duo Liu, MD, Masahiro Hatemura, RT, Yoshinori Funama, PhD, Shoji Morishita, MD and Yasuyuki Yamashita, MD

1 From the Department of Diagnostic Radiology, Graduate School of Medical Sciences, Kumamoto University, 1-1-2 Honjyo, Kumamoto 860-8556, Japan. Received January 13, 2006; revision requested March 10; revision received April 25; accepted May 31; final version accepted August 1. Address correspondence to K.A.


Figure 1
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Figure 1: Histogram shows distribution of times required to reach the trigger threshold in patients. Mean interval was 19.4 seconds ± 3.4 (range, 12–34 seconds).

 

Figure 2
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Figure 2: Aortic enhancement values for five scan protocols, shown as means ± SDs. Multiple comparisons were performed with the Dunnett method; enhancement values for protocol A served as the control.

 

Figure 3
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Figure 3: Liver enhancement values for five scan protocols, shown as means ± SDs. Multiple comparisons were performed with the Dunnett method; enhancement values for protocol A served as the control.

 

Figure 4
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Figure 4: Portal vein enhancement values for five scan protocols, shown as means ± SDs. Multiple comparisons were performed with the Dunnett method; enhancement values for protocol A served as the control.

 

Figure 5
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Figure 5: TLC values for five scan protocols, shown as means ± SDs. Multiple comparisons were performed with the Dunnett method; TLC values for protocol A served as the control.

 

Figure 6A
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Figure 6a: (a) Transverse CT image at level of left portal vein in a 64-year-old man with HCC, scanned according to protocol A. TLC in this patient was 27.6 HU (mean TLC for protocol A, 23.4 HU). (b) Transverse CT image at level of left portal vein in a 69-year-old man with HCC, scanned according to protocol B. TLC in this patient was 38.2 HU (mean TLC for protocol B, 35.5 HU). (c) Transverse CT image at level of porta hepatis in a 64-year-old man with HCC, scanned according to protocol C. TLC in this patient was 33.3 HU (mean TLC for protocol C, 36.2 HU). (d) Transverse CT image at level of porta hepatis in a 58-year-old man with HCC, scanned according to protocol D. TLC in this patient was 53.2 HU (mean TLC for protocol D, 47.2 HU). (e) Transverse CT image at level of superior pole of left kidney in a 62-year-old woman with HCC, scanned according to protocol E. TLC in this patient was 36.4 HU (mean TLC for protocol E, 35.1 HU). Arrow in a–e indicates hypervascular HCC.

 

Figure 6B
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Figure 6b: (a) Transverse CT image at level of left portal vein in a 64-year-old man with HCC, scanned according to protocol A. TLC in this patient was 27.6 HU (mean TLC for protocol A, 23.4 HU). (b) Transverse CT image at level of left portal vein in a 69-year-old man with HCC, scanned according to protocol B. TLC in this patient was 38.2 HU (mean TLC for protocol B, 35.5 HU). (c) Transverse CT image at level of porta hepatis in a 64-year-old man with HCC, scanned according to protocol C. TLC in this patient was 33.3 HU (mean TLC for protocol C, 36.2 HU). (d) Transverse CT image at level of porta hepatis in a 58-year-old man with HCC, scanned according to protocol D. TLC in this patient was 53.2 HU (mean TLC for protocol D, 47.2 HU). (e) Transverse CT image at level of superior pole of left kidney in a 62-year-old woman with HCC, scanned according to protocol E. TLC in this patient was 36.4 HU (mean TLC for protocol E, 35.1 HU). Arrow in a–e indicates hypervascular HCC.

 

Figure 6C
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Figure 6c: (a) Transverse CT image at level of left portal vein in a 64-year-old man with HCC, scanned according to protocol A. TLC in this patient was 27.6 HU (mean TLC for protocol A, 23.4 HU). (b) Transverse CT image at level of left portal vein in a 69-year-old man with HCC, scanned according to protocol B. TLC in this patient was 38.2 HU (mean TLC for protocol B, 35.5 HU). (c) Transverse CT image at level of porta hepatis in a 64-year-old man with HCC, scanned according to protocol C. TLC in this patient was 33.3 HU (mean TLC for protocol C, 36.2 HU). (d) Transverse CT image at level of porta hepatis in a 58-year-old man with HCC, scanned according to protocol D. TLC in this patient was 53.2 HU (mean TLC for protocol D, 47.2 HU). (e) Transverse CT image at level of superior pole of left kidney in a 62-year-old woman with HCC, scanned according to protocol E. TLC in this patient was 36.4 HU (mean TLC for protocol E, 35.1 HU). Arrow in a–e indicates hypervascular HCC.

 

Figure 6D
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Figure 6d: (a) Transverse CT image at level of left portal vein in a 64-year-old man with HCC, scanned according to protocol A. TLC in this patient was 27.6 HU (mean TLC for protocol A, 23.4 HU). (b) Transverse CT image at level of left portal vein in a 69-year-old man with HCC, scanned according to protocol B. TLC in this patient was 38.2 HU (mean TLC for protocol B, 35.5 HU). (c) Transverse CT image at level of porta hepatis in a 64-year-old man with HCC, scanned according to protocol C. TLC in this patient was 33.3 HU (mean TLC for protocol C, 36.2 HU). (d) Transverse CT image at level of porta hepatis in a 58-year-old man with HCC, scanned according to protocol D. TLC in this patient was 53.2 HU (mean TLC for protocol D, 47.2 HU). (e) Transverse CT image at level of superior pole of left kidney in a 62-year-old woman with HCC, scanned according to protocol E. TLC in this patient was 36.4 HU (mean TLC for protocol E, 35.1 HU). Arrow in a–e indicates hypervascular HCC.

 

Figure 6E
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Figure 6e: (a) Transverse CT image at level of left portal vein in a 64-year-old man with HCC, scanned according to protocol A. TLC in this patient was 27.6 HU (mean TLC for protocol A, 23.4 HU). (b) Transverse CT image at level of left portal vein in a 69-year-old man with HCC, scanned according to protocol B. TLC in this patient was 38.2 HU (mean TLC for protocol B, 35.5 HU). (c) Transverse CT image at level of porta hepatis in a 64-year-old man with HCC, scanned according to protocol C. TLC in this patient was 33.3 HU (mean TLC for protocol C, 36.2 HU). (d) Transverse CT image at level of porta hepatis in a 58-year-old man with HCC, scanned according to protocol D. TLC in this patient was 53.2 HU (mean TLC for protocol D, 47.2 HU). (e) Transverse CT image at level of superior pole of left kidney in a 62-year-old woman with HCC, scanned according to protocol E. TLC in this patient was 36.4 HU (mean TLC for protocol E, 35.1 HU). Arrow in a–e indicates hypervascular HCC.

 





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