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DOI: 10.1148/radiol.2451061116
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Computer-aided Detection of Colorectal Polyps: Can It Improve Sensitivity of Less-Experienced Readers? Preliminary Findings1

Mark E. Baker, MD, Luca Bogoni, PhD, Nancy A. Obuchowski, PhD, Chandra Dass, MD, Renee M. Kendzierski, DO, Erick M. Remer, MD, David M. Einstein, MD, Pascal Cathier, PhD, Anna Jerebko, PhD, Sarang Lakare, PhD, Andrew Blum, MD, Dina F. Caroline, MD, PhD, and Michael Macari, MD

1 From the Departments of Radiology and Quantitative Health Sciences, the Cleveland Clinic Foundation, 9500 Euclid Ave, Hb6, Cleveland, OH 44195 (M.E.B., N.A.O., E.M.R., D.M.E.); Department of Radiology, Temple University, Philadelphia, Pa (C.D., R.M.K., A.B., D.F.C.); Department of Radiology, New York University School of Medicine, New York, NY (M.M.); and Siemens Medical Systems, Malvern, Pa (L.B., P.C., A.J., S.L.). From the 2005 RSNA Annual Meeting. Received June 29, 2006; revision requested September 1; revision received October 25; accepted November 22; final version accepted April 2, 2007. Address correspondence to M.E.B. (e-mail: bakerm{at}ccf.org).


Figure 1
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Figure 1: Flow diagram shows total CT colonographic population used for the investigation and for partitioning the CT studies into groups for CAD training, physician demonstration and training, and testing of CAD. Target condition present = at least one polyp larger than 6 mm.

 

Figure 2
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Figure 2: Individual polyp detection by readers alone ({blacksquare}) and with CAD ({circ}), as well as polyps missed by reader or CAD. The frequency shows how often a given polyp of a specific size was detected by readers and with CAD. For instance, on the x-axis, looking at one 6-mm polyp (there were three polyps of this size), we can see that it was detected with CAD (C Found) and by all seven readers; a 7.0-mm polyp was missed with CAD (C Missed) but was detected by all readers. Finally, all polyps but one in the range 6.0–9.3 mm were detected with CAD; some were detected by as many as seven or as few as four readers. R Missed = individual polyp missed by a reader.

 

Figure 3
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Figure 3: CT colonographic images show transverse two-dimensional (left) and endoluminal three-dimensional (right) views of a 7.4-mm polyp in the transverse colon (2b marks polyp identified by one reader). The polyp was found with CAD but was rejected by two readers.

 

Figure 4
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Figure 4: CT colonographic images show transverse two-dimensional (left) and endoluminal three-dimensional (right) views of a 9.8-mm polyp in the cecum (3b marks polyp identified by one reader). The polyp was missed or dismissed by both readers and CAD.

 

Figure 5
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Figure 5: Graph shows mean reader time plus mean time to review CAD findings. Ave = mean time for the seven readers.

 





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