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Coronary Arteries: Diagnostic Performance of 16- versus 64-Section Spiral CT Compared with Invasive Coronary Angiography—Meta-Analysis¹

¹ From the Departments of Radiology (Michèle Hamon), Statistics (R.M.), and Cardiology (J.W.R., Martial Hamon), University Hospital of Caen, Avenue Côte de Nacre, 14033 Caen Cedex, Normandy, France. Received November 6, 2006; revision requested January 10, 2007; revision received February 5; accepted March 16; final version accepted May 1. Address correspondence to Michèle Hamon (e-mail: hamon-mi{at}chu-caen.fr).

View larger version (28K): [in this window] [in a new window] [Download PPT slide]   Figure 1: Flow diagram of the reviewing process.

View larger version (15K): [in this window] [in a new window] [Download PPT slide]   Figure 2: Diagnostic performance of 16-section CT (white bars) compared with 64-section CT (black bars) on a per-segment basis (P < .001 for all).

View larger version (15K): [in this window] [in a new window] [Download PPT slide]   Figure 3: Diagnostic performance of 16-section CT (white bars) compared with 64-section CT (black bars) on a per-patient basis (P = .03 for sensitivity, P < .001 for the other values).

View larger version (28K): [in this window] [in a new window] [Download PPT slide]   Figure 4: Plot of symmetric summary receiver operating characteristic (SROC) on a per-patient basis for comparison of multisection CT with coronary angiography. Left: 16-section CT. Right: 64-section CT. The receiver operating characteristic curve provides a graphical display of diagnostic accuracy, by plotting specificity subtracted from one on the horizontal axis and sensitivity on the vertical axis. The pertinent area under the curve (AUC) and Cochran Q statistic (Q*) (the point where sensitivity and specificity are maximal), both with standard errors (SE), are also included.