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Figure 1b. Pituitary gland volumes in 14 patients. Graphs show (a) volume 1 and (b) volume 2 for the euthyroid and hypothyroid states. The hypothyroid state was associated with significantly larger pituitary gland volumes (volume 1 = 453 mm³ ± 109, volume 2 = 626 mm³ ± 173) than was the euthyroid state (volume 1 = 331 mm³ ± 68, volume 2 = 453 mm³ ± 107). Two (patients 2 and 7) of the 14 patients had the same volume 1 (385 mm³ for the euthyroid state and 539 mm³ for the hypothyroid state). In a and b, • indicates the calculated pituitary gland volume, indicates the mean, and the vertical bar indicates the SD.