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Figure 4b. Images show cardiac enhancement with SH U 555 C and perfusion. (a) Graph shows that short-axis cardiac perfusion images with 40 µmol Fe/kg dose have an early peak at 7 seconds within the right ventricle, followed by an SI decrease at 12 seconds with a second pass and subsequent stable equilibrium phase after 30 seconds. Left ventricle demonstrates first peak at 12 seconds, followed by SI decrease at 19 seconds, second peak at 26 seconds, and subsequent equilibrium phase with continuous (not significant) SI increase during time. Enhancement (ENH) within myocardium of left ventricle shows initial increase during first pass, with maximum at 23 seconds followed by small decrease and subsequent stable equilibrium phase after 30 seconds. Enhancement within left ventricle = A – ENH LV, within right ventricle = B – ENH RV, and within left ventricular myocardium = C – ENH LV Myocard. (b) Short-axis T1-weighted turbo fast low-angle shot MR images (416/1.2/200; delay, 50 msec; flip angle, 8o; time resolution, one image per second) obtained at different times (top left to bottom right) after SH U 555 C (40 µmol Fe/kg) injection show cardiac perfusion. Images show time course with inflow into right and left ventricles and myocardial enhancement. Enhancement within right ventricle with subsequent passage through pulmonary circulation is followed by enhancement within left ventricle and myocardium. pre = precontrast image. (c) Color-coded mean transit time map with homogeneous signal throughout myocardium. Cardiac perfusion data sets obtained at 40 µmol Fe/kg were postprocessed, and parameter maps were generated to test for feasibility of calculation of maps. Images may be used to visualize regional perfusion changes within myocardium.
