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Figure 1c. M avium-intracellulare complex infection in 52-year-old woman. Transverse thin-section (2.5-mm collimation) CT scans obtained at levels of (a) right lower lobar bronchus and (b) right inferior pulmonary vein show cavitary consolidation, small nodules (arrow), and branching centrilobular nodules (ie, tree-in-bud pattern) (arrowhead) in right lower lobe. (c) Right lower lobectomy specimen shows several granulomas with caseating material. One of the granulomas created a central necrotic cavity (arrow). Bronchial wall destruction (arrowhead) due to inflammation and granulomatous change also is apparent. (d) Low-magnification photomicrograph shows well-defined granuloma (arrow) around an inflamed bronchiole (B). Also note the Langhans-type giant cells (arrowheads). (Hematoxylin-eosin stain; original magnification, x40.)
