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Figure 5b. Transverse CT images of accelerated UIP in a 78-year-old man with rapidly progressive shortness of breath. (a) Baseline image shows subpleural reticular pattern and honeycombing (arrows), with ground-glass opacity in remainder of the lung. (b) Five months later, after 4 weeks of progressive breathlessness, progression of honeycombing and extensive new ground-glass opacification are shown. Biopsy specimen showed organizing pneumonia pattern superimposed on background UIP. Patient responded to aggressive immunosuppressive treatment.
