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Figure 10: Four-dimensional US images of breast in a 39-year-old woman with stage T2 cancer (arrow) in the left breast. Left: Cancer initially measured 24 x 12 x 19 mm. Patient was examined with combined three-dimensional US and digital mammography research system being developed at the University of Michigan (Ann Arbor, Mich) in partnership with GE Global Research. Right: Scans obtained after completion of four cycles of neoadjuvant chemotherapy. By viewing nearly whole breast image volumes, it is easier to localize any posttreatment remains of tumor and to judge treatment success, hopefully with automatic volume change measurements. Such four-dimensional imaging may revolutionize three-dimensional US screening for breast cancer, allowing precise section-by-section or pixel-by-pixel visual comparison. Ant = anterior, Lat = lateral, Med = medial, Post = posterior. (Image courtesy of Charles Meyer, PhD, and Paul Carson, PhD, University of Michigan, Ann Arbor, Mich)