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Figure 1b: Macroadenoma with soft consistency in 46-year-old woman. (a) Coronal spin-echo T2-weighted MR image (3000/110) shows large inhomogeneous isointense pituitary mass (arrows). (b) Coronal DW single-shot spin-echo echo-planar MR image (5000/101) with diffusion gradient in three principal orthogonal axes and b values of 0 and 1000 sec/mm2 shows hyperintense mass (arrows) with respect to normal white matter. (c) Coronal ADC map shows mass (arrows) with decreased diffusion coefficient of (0.593 ± 0.126) x 103 mm2/sec. (d) Specimen of mass at histologic examination shows small cells (in blue) with scant fibrous stroma (in red). (Sirius red stain; original magnification, x20.)