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Figure 6c: Use of rCBV map to determine optimal biopsy site in a 44-year-old woman with seizures who was suspected of having a brain tumor. Subsequent biopsy showed World Health Organization grade III astrocytoma. (a) Transverse T2-weighted MR image shows hyperintense region (arrow) in left frontal lobe. (b) Transverse contrast-enhanced T1-weighted MR image shows no areas of abnormal contrast enhancement, making determination of region of optimal biopsy site difficult. (c) rCBV map obtained with DSC technique (red and yellow = high rCBV, green and blue = low rCBV). A high rCBV area (arrow) corresponds to region of hyperintense abnormality in a. At biopsy, this region was shown to represent high-grade glioma. (Reprinted, with permission, from reference 30.)
