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Figure 1a: Coronal sections from ventilation 3He MR images (6/2.5, 128 x 128 matrix, 1.0-cm section thickness,
10° flip angle) demonstrate typical defects (arrows) that were classified in each descriptive category in Table 1. (a) Subject 13. No defects in a smoker with 14 pack-years of smoking. (b) Subject 1. Small peripheral defects in a nonsmoker. (c) Subject 19. Large peripheral defects in a smoker with 39 pack-years of smoking.