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Figure 4: Medial left frontal lobe well-differentiated astrocytoma in 30-year-old man. Transverse functional MR images derived from series of T2*-weighted echo-planar MR images (2000/40, 24 x 24-m field of view, 64 x 64 matrix, 5-m section thickness, no intersection gap) are displayed as thresholded activation maps overlaid in red and yellow on a set of coplanar transverse T2-weighted fast spin-echo MR images (3000/84, 24 x 24-cm field of view, 256 x 192 matrix, 5-mm section thickness, no intersection gap, echo train length of eight). Craniotomy with general anesthesia was planned, with lesion presumed to be sufficiently removed from expressive speech areas. Left inferior frontal gyral activation (yellow arrows) is consistent with dominant expressive speech area located 1 cm inferolateral to posterior margin of left frontal lobe lesion. Left superior and middle temporal gyral activation (green arrows) is consistent with dominant receptive speech area, is located inferiorly, and is separated from left frontal lobe lesion by sylvian fissure. Imaging results helped confirm existing treatment plan. No postoperative neurologic deficits were documented.