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Figure 8c: (a) Graph shows 111In-oxine–labeled donor cell localization in recipient apolipoprotein E–deficient atherosclerotic mice (ApoE–/–) versus that in WT control mice, as determined with whole-body SPECT at 7 days. Localization to BM was significantly (P = .02) higher in apolipoprotein E–deficient mice than in control mice. In contrast, localization to the spleen and liver (P = .04 and P = .02, respectively) was significantly lower in apolipoprotein E–deficient mice than in control mice. (b, c) Graphs show linear correlation for whole-body 111In-oxine activity per organ, as determined with gamma counts and SPECT in apolipoprotein E–deficient (b) and control (c) mice. Activity determined with SPECT shows good correlation with activity determined with gamma well counting for apolipoprotein E–deficient and control mice (r = 0.92 and = 0.91, respectively).
