Feature

All

Invasive Tumors

(n = 64)

Moderate Risk

(n = 18)

High
Risk

(n = 27)

Mutation Carriers

BRCA1

(n = 14)

BRCA2

(n = 5)

Negative (BI-RADS 1, 2)

27 (42%)

10 (56%)

10 (37%)

6 (43%)

1 (20%)

Positive (BI-RADS 3, 4, 5)

37 (58%)

8 (44%)

17 (63%)

8 (57%)

4 (80%)

Mass

14 (21%)

3 (17%)

6 (22%)

4 (29%)

1 (20%)

Shape

Round

4 (6%)

-

1 (4%)

3 (21%)

-

Oval

3 (5%)

-

3 (11%)

-

-

Lobular

-

-

-

-

-

Irregular

7 (11%)

3 (17%)

2 (7%)

1(7%)

1 (20%)

Margin

Circumscribed

4 (6%)

-

3 (11%)

1 (7%)

-

Microlobulated

1 (2%)

-

-

1 (7%)

-

Obscured

3 (5%)

1 (6%)

1 (4%)

1 (7%)

-

Indistinct

6 (9%)

2 (11%)

2 (7%)

1 (7%)

1 (20%)

Density

High

12 (19%)

1 (6%)

6 (22%)

4 (29%)

1 (20%)

Equal (isodense)

2 (3%)

2 (11%)

-

-

-

Low (no fat)

-

-

-

-

-

Architectural distortion

6 (9%)

1 (6%)

1 (4%)

3 (21%)

1 (20%)

Microcalcifications

12 (19%)

3 (17%)

7 (26%)

-

2 (40%)

1. Typically benign

-

-

-

-

-

2. Intermediate/suspicious calcifications

2 (3%)

2 (11%)

-

-

-

Amorphous or indistinct

1 (2%)

1 (6%)

-

-

-

Coarse heterogeneous

1 (2%)

1 (6%)

-

-

-

3. Higher probability of malignancy

10 (16%)

1 (6%)

7 (26%)

-

2 (40%)

Fine pleomorphic

7 (11%)

1 (6%)

5 (19%)

-

1 (20%)

Fine linear

3 (5%

-

2 (7%)

-

1(20%)

4. Distribution modifiers

Regional

3 (5%)

1 (6%)

1 (4%)

-

1 (20%)

Grouped/clustered

4 (6%)

-

3 (11%)

-

1 (20%)

Linear/ductal

2 (3%)

1 (6%)

1 (4%)

-

-

Segmental

3 (5%)

1 (6%)

2 (7%)

-

-

Mass with microcalcifications

5 (8%)

1 (6%)

3 (11%)

1 (7%)

-

Feature

All
Invasive Tumors

(n = 64)

Moderate Risk

(n = 18)

High
Risk

(n = 27)

Mutation Carriers