Reference No.

Country

Year

No. of Patients

Mean age (y)

Prevalence of Cancer (%)*

Prevalence of Palpable Lesions (%)*

Prevalence of Invasive Ductal Carcinoma (%)^†

Type of Contrast Agent Used^‡

Dose of Contrast Agent Used^§

Criteria for Malignancy Reported

No. of Criteria for Malignancy Used

Threshold Set

Appropriate Reference Standard Used (%)

No. of Reference Standards

Blinding for histology

Blinding for clinical information

Lesion-to-patient ratio

15

Germany

2001

14

49

64 (9/14)

NA

78 (7/9)

1

1

Yes

3

Before

100 (14/14)

1

Yes

NA

1

16

Korea

2002

25

51

28 (7/25)

68 (17/25)

100 (7/7)

1

2

Yes

3

Before

84 (21/25)

3

NA

Yes

1

17

Italy

2002

28

NA

54 (15/28)

NA

47 (7/15)

1

1

Yes

3

Before

100 (28/28)

1

NA

NA

1

18

Ireland

1995

31

NA

52 (16/31)

NA

75 (12/16)

1

1

No

NA

NA

100 (31/31)

1

Yes

Yes

1

19

Japan

1999

34

54

59 (20/34)

82 (28/24)

NA

1

1

Yes

3

Before

100 (34/34)

1

Yes

NA

1

20

U.S.

2001

38

49

61 (23/38)

NA

78 (18/23)

1

1

No

NA

NA

100 (38/38)

1

NA

No

1

21

U.S.

1994

39

NA

38 (15/39)

NA

53 (8/15)

1

1

Yes

1

Before

100 (39/39)

1

Yes

NA

1NA11

22

Germany

1998

40

52

55 (22/40)

38 (15/40)

64 (14/22)

1

1

Yes

2

Before

100 (40/40)

1

Yes

Yes

1

23

Germany

2001

40

48

57 (23/40)

NA

83 (19/23)

1

1

Yes

2

Before

100 (40/40)

1

NA

NA

1

24

Finland

2002

40

49

63 (25/40)

55 (22/40)

60 (15/25)

1

2

Yes

1

Before

100 (40/40)

1

NA

No

1NA05

25

Austria

2003

40

48

63 (25/40)

NA

80 (20/25)

1

2

Yes

2

Before

100 (40/40)

1

NA

No

1NA11

26

U.S.

1997

43

50

47 (20/43)

NA

NA

1

2

No

NA

NA

100 (43/43)

1

NA

NA

1

27

Italy

2003

45

51

84 (38/45)

NA

NA

1

NA

Yes

3

Before

84 ((38/45)

2

NA

NA

1

28

U.K.

2004

49

49

65 (32/49)

02 (1/43)

NA

1

1

No

NA

NA

100 (49/49)

2

NA

NA

1NA14

29

U.S.

2004

50

50

36 (18/50)

NA