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1 From the Department of Radiology, Stanford University School of Medicine, 300 Pasteur Dr, SO-68B, Stanford, CA 94305-5105 (G.E.G., S.B.R., H.Y., N.J.P., C.F.B.); Department of Radiology, University of Leiden, Leiden, the Netherlands (P.K.); and GE Healthcare Applied Sciences Laboratory West, Menlo Park, Calif (A.S.S., J.W.J., J.H.B.). Received February 18, 2005; revision requested April 19; revision received August 26; accepted September 22; final version accepted October 19. Supported by NIH grant EB002524-01 and the Whitaker Foundation. Address correspondence to G.E.G. (e-mail: gold{at}stanford.edu).
Institutional review board approval and informed consent were obtained for this HIPAA-compliant study. In this study, iterative decomposition of water and fat with echo asymmetry and least-squares estimation (IDEAL) balanced steady-state free precession (bSSFP), fat-suppressed bSSFP, and fat-suppressed spoiled gradient-echo (GRE) sequences for 3.0-T magnetic resonance (MR) imaging of articular knee cartilage were prospectively compared in five healthy volunteers. Cartilage and fluid signal-to-noise ratio (SNR), cartilage-fluid contrast-to-noise ratio (CNR), SNR efficiency, CNR efficiency, image quality, and fat suppression were compared. Fat-suppressed bSSFP and IDEAL bSSFP had higher SNR efficiency of cartilage (P < .01) than did GRE. IDEAL bSSFP had higher cartilage-fluid CNR efficiency than did fat-suppressed bSSFP or GRE (P < .01). Fat-suppressed bSSFP and IDEAL bSSFP had higher image quality than did GRE (P < .01). GRE and IDEAL bSSFP had significantly better fat-water separation or fat saturation than did fat-suppressed bSSFP (P < .05). IDEAL bSSFP is a promising method for imaging articular knee cartilage.
© RSNA, 2006
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