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Cardiovascular Molecular Imaging¹

¹ From the Department of Medicine, Division of Cardiology (J.C.W.), Department of Radiology, Molecular Imaging Program at Stanford (J.C.W., S.S.G.), and Bio-X Program (S.S.G.), Stanford University, 300 Pasteur Dr, Edwards Bldg R354, Stanford, CA 94305-5344; and Department of Nuclear Medicine, Johns Hopkins University, Baltimore, Md (F.M.B.). Received January 25, 2006; revision requested March 24; revision received April 7; final version accepted June 1. Address correspondence to J.C.W. (e-mail: joewu{at}stanford.edu).

The goal of this review is to highlight how molecular imaging will impact the management and improved understanding of the major cardiovascular diseases that have substantial clinical impact and research interest. These topics include atherosclerosis, myocardial ischemia, myocardial viability, heart failure, gene therapy, and stem cell transplantation. Traditional methods of evaluation for these diseases will be presented first, followed by methods that incorporate conventional and molecular imaging approaches.