Radiology -- Table of Contents (244 [2])

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SCIENCE TO PRACTICE:

David B. Hackney: Does MR Imaging Improve Precision in Stroke Thrombolysis Trials?
Their results demonstrate the ability to identify the ischemic and putatively infarcted regions before therapy, to institute therapy in a model that compares thrombolytic agents, and to document the response and complication rates.
Radiology 2007 244: 323-324 (DOI: 10.1148/radiol.2442062193); [Figures Only] [Full Text] [PDF]

COMMUNICATIONS:

Letters to the Editor:

Murray L. Janower: Public Relations
Radiology 2007 244: 622 (DOI: 10.1148/radiol.2442062077); [Full Text] [PDF]

Ulf Nyman, Barbara Elmståhl, and Peter Leander: Suggesting Gadolinium-based Contrast Media for CT in Azotemic Patients Is Not Based on Historical, Clinical, and Experimental Data
Radiology 2007 244: 622-623 (DOI: 10.1148/radiol.2442061485); [Full Text] [PDF]

Andrew Scarsbrook, Kevin Bradley, Fergus Gleeson, Ashley M. Groves, Stuart J. Yates, Thida Win, Irfan Kayani, Jamshed Bomanji, and Peter J. Ell: Perfusion Scintigraphy Still has Important Role in Evaluation of Majority of Pregnant Patients with Suspicion of Pulmonary Embolism
Radiology 2007 244: 623-625 (DOI: 10.1148/radiol.2442061511); [Full Text] [PDF]

Kwok-Man Tong, Tu-Sheng Lee, Yu-Min Lin, and Christian W. A. Pfirrmann: Cam and Pincer Impingements Rarely Occur in Isolation
Radiology 2007 244: 625-626 (DOI: 10.1148/radiol.2442061498); [Full Text] [PDF]

Erratum:

: Erratum
Radiology 2007 244: 626 (DOI: 10.1148/radiol.2442072531); [Full Text] [PDF]

REVIEWS AND COMMENTARY:

Editorials:

Olga R. Brook: Recollections of a Radiology Resident at War
Nothing prepares one for war—it defies professional detachment.
Radiology 2007 244: 329-330 (DOI: 10.1148/radiol.2442061881); [Full Text] [PDF]

Evidence-based Radiology Series:

L. Santiago Medina and C. Craig Blackmore: Evidence-based Radiology: Review and Dissemination
Although radiology has made important progress in the field of evidence-based medicine in recent years, our specialty is still behind other specialties that have been at the forefront of this field in the past decade.
Radiology 2007 244: 331-336 (DOI: 10.1148/radiol.2442051766); [Abstract] [Full Text] [PDF]

Molecular Imaging Series:

Joseph C. Wu, Frank M. Bengel, and Sanjiv S. Gambhir: Cardiovascular Molecular Imaging
By using standard anatomic imaging modalities combined with molecular imaging technologies such as SPECT and PET, we now have the potential to detect disease processes at the anatomic, physiologic, metabolic, and molecular levels and, thereby, allow (a) earlier detection of diseases, (b) objective monitoring of therapies, and (c) better prognostication of disease progression.
Radiology 2007 244: 337-355. Published online before print June 25 2007, 10.1148/radiol.2442060136 [Abstract] [Figures Only] [Full Text] [PDF]

State of the Art:

Christiane Kuhl: The Current Status of Breast MR Imaging • Part I. Choice of Technique, Image Interpretation, Diagnostic Accuracy, and Transfer to Clinical Practice
Breast imaging fellowship programs should embrace MR as a natural component of the contemporary breast imaging armamentarium and train breast radiologists to become competent MR users—only as far as breast imaging is concerned, but in the broadest sense of the word.
Radiology 2007 244: 356-378 (DOI: 10.1148/radiol.2442051620); [Abstract] [Figures Only] [Full Text] [PDF]

Perspectives:

James H. Thrall: Teleradiology • Part II. Limitations, Risks, and Opportunities
It is likely that major consolidation in the practice of radiology will be fostered by means of teleradiology to achieve benefits of scale, provide more timely service, provide access to subspecialist clinical expertise, and better match supply with demand.
Radiology 2007 244: 325-328 (DOI: 10.1148/radiol.2442070676); [Full Text] [PDF]

Book Reviews:

: Mammography Casebook: 100 Studies in Breast Imaging
Radiology 2007 244: 379 (DOI: 10.1148/radiol.2442072522); [Full Text] [PDF]

: Fracture Classifications in Clinical Practice
Radiology 2007 244: 379-380 (DOI: 10.1148/radiol.2442072523); [Full Text] [PDF]

: Positron Emission Tomography: Clinical Practice
Radiology 2007 244: 380 (DOI: 10.1148/radiol.2442072524); [Full Text] [PDF]

: Teaching Atlas of Interventional Radiology: Non-Vascular Interventional Procedures
Radiology 2007 244: 380 (DOI: 10.1148/radiol.2442072525); [Full Text] [PDF]

ORIGINAL RESEARCH:

Breast Imaging:

Constance D. Lehman, Claudine Isaacs, Mitchell D. Schnall, Etta D. Pisano, Susan M. Ascher, Paul T. Weatherall, David A. Bluemke, Deborah J. Bowen, P. Kelly Marcom, Deborah K. Armstrong, Susan M. Domchek, Gail Tomlinson, Steven J. Skates, and Constantine Gatsonis: Cancer Yield of Mammography, MR, and US in High-Risk Women: Prospective Multi-Institution Breast Cancer Screening Study
Our multi-institutional study further supports MR as an important complement to mammography in screening women at high risk for breast cancer.
Radiology 2007 244: 381-388 (DOI: 10.1148/radiol.2442060461); [Abstract] [Figures Only] [Full Text] [PDF]

Jonathan L. Jesneck, Joseph Y. Lo, and Jay A. Baker: Breast Mass Lesions: Computer-aided Diagnosis Models with Mammographic and Sonographic Descriptors
The results of model classification and generalization performance on our data set suggest that the models could be used as a computer-aided diagnosis system for future mass lesions.
Radiology 2007 244: 390-398. Published online before print June 11 2007, 10.1148/radiol.2442060712 [Abstract] [Figures Only] [Full Text] [PDF]

Cardiac Imaging:

Michael Fenchel, Roya Saleh, Howard Dinh, Margaret H. Lee, Kambiz Nael, Mayil Krishnam, Stefan G. Ruehm, Stephan Miller, John Child, and J. Paul Finn: Juvenile and Adult Congenital Heart Disease: Time-resolved 3D Contrast-enhanced MR Angiography
By defining visually the sequence of enhancement of the central blood vessels, lungs, and cardiac chambers, time-resolved MR angiography provides functional and anatomic information that complements or supplements that provided by conventional MR angiography and cardiac cine imaging.
Radiology 2007 244: 399-410 (DOI: 10.1148/radiol.2442061045); [Abstract] [Figures Only] [Full Text] [PDF]

Monravee Tumkosit, Carla G. Martin, Ersin Bayram, Timothy M. Morgan, Kimberly S. Lane, Pairoj Rerkpattanapipat, Craig A. Hamilton, Kerry M. Link, and W. Gregory Hundley: Left Ventricular Spherical Remodeling and Apical Myocardial Relaxation: Cardiovascular MR Imaging Measurement of Myocardial Segments
In participants with spherical remodeling of the left ventricle (sphericity index, <1.5), left ventricular diastolic relaxation in the apical segments was reduced compared with that in healthy participants with a left ventricle in the shape of a prolate ellipse (sphericity index, $≥$ 1.5).
Radiology 2007 244: 411-418 (DOI: 10.1148/radiol.2442060780); [Abstract] [Figures Only] [Full Text] [PDF]

Evidence-based Practice:

Piet K. Vanhoenacker, Majanka H. Heijenbrok-Kal, Ruben Van Heste, Isabel Decramer, Lieven R. Van Hoe, William Wijns, and M. G. Myriam Hunink: Diagnostic Performance of Multidetector CT Angiography for Assessment of Coronary Artery Disease: Meta-analysis
With the newer generations of multidetector CT scanners, the diagnostic performance for the assessment of significant coronary arterial stenoses (>50%-diameter stenosis) has significantly improved (P < .05) and the proportion of nonassessable segments has decreased.
Radiology 2007 244: 419-428 (DOI: 10.1148/radiol.2442061218); [Abstract] [Figures Only] [Full Text] [PDF] [Appendix E1][Appendix E2][Table E1]

Experimental Studies:

Feng Chen, Yasuhiro Suzuki, Nobuo Nagai, Xihe Sun, Huaijun Wang, Jie Yu, Guy Marchal, and Yicheng Ni: Microplasmin and Tissue Plasminogen Activator: Comparison of Therapeutic Effects in Rat Stroke Model at Multiparametric MR Imaging
A multiparametric MR imaging approach allows noninvasive assessment of the therapeutic effects and hemorrhagic transformation after administration of antistroke agents.
Radiology 2007 244: 429-438. Published online before print June 20 2007, 10.1148/radiol.2442061316 [Abstract] [Figures Only] [Full Text] [PDF]

Charlotte Rivière, Marie-Sophie Martina, Yutaka Tomita, Claire Wilhelm, Alexy Tran Dinh, Christine Ménager, Elisabeth Pinard, Sylviane Lesieur, Florence Gazeau, and Jacques Seylaz: Magnetic Targeting of Nanometric Magnetic Fluid–loaded Liposomes to Specific Brain Intravascular Areas: A Dynamic Imaging Study in Mice
With application of the magnet, no static fluorescence was observed in the arterioles, while the concentration of rhodamine-labeled magnetic fluid–loaded liposomes in the capillaries and venules increased gradually in a two-phase manner.
Radiology 2007 244: 439-448. Published online before print June 11 2007, 10.1148/radiol.2442060912 [Abstract] [Figures Only] [Full Text] [PDF] [Appendices]

Thorsten Persigehl, Ralf Bieker, Lars Matuszewski, Alexander Wall, Torsten Kessler, Hendrik Kooijman, Norbert Meier, Wolfgang Ebert, Wolfgang E. Berdel, Walter Heindel, Rolf M. Mesters, and Christoph Bremer: Antiangiogenic Tumor Treatment: Early Noninvasive Monitoring with USPIO-enhanced MR Imaging in Mice
Our study data suggest that ultrasmall superparamagnetic iron oxide–enhanced MR imaging may help to quantify changes in tumor perfusion in response to antiangiogenic treatment.
Radiology 2007 244: 449-456. Published online before print June 11 2007, 10.1148/radiol.2442060371 [Abstract] [Figures Only] [Full Text] [PDF]

Marc Kalinowski, Kai Goldmann, Martin Gotthardt, Marion Rössler, Andreas Pfestroff, Klaus Jochen Klose, and Hans-Joachim Wagner: Effectiveness and Renal Tolerance of Multidetector Helical CT with Gadobutrol: Results of a Comparative Porcine Study
Intravenous administration of high doses of gadobutrol did not affect renal function in these animals.
Radiology 2007 244: 457-463. Published online before print June 11 2007, 10.1148/radiol.2441060354 [Abstract] [Figures Only] [Full Text] [PDF]

Antoine Hakimé, Andrew Hines-Peralta, Himaja Peddi, Michael B. Atkins, Vikas P. Sukhatme, Sabina Signoretti, Meredith Regan, and S. Nahum Goldberg: Combination of Radiofrequency Ablation with Antiangiogenic Therapy for Tumor Ablation Efficacy: Study in Mice
Our results suggest that pretreatment of renal cell carcinoma tumors in nude mice with the antiangiogenic agent sorafenib can decrease tumor microvascular density and substantially enhance radiofrequency ablation in a dose-dependent manner.
Radiology 2007 244: 464-470 (DOI: 10.1148/radiol.2442061005); [Abstract] [Figures Only] [Full Text] [PDF]

Gastrointestinal Imaging:

Laurian Copel, Jacob Sosna, Jonathan B. Kruskal, Vassilios Raptopoulos, Richard J. Farrell, and Martina M. Morrin: CT Colonography in 546 Patients with Incomplete Colonoscopy
CT colonography after incomplete colonoscopy has per-patient and per-lesion PPVs of 90.9% and 91.7%, respectively, for masses and 64.7% and 70%, respectively, for polyps of 10 mm or larger but led to overcalls for one of three large ( $≥$ 10-mm) polyps and two of three medium (6–9-mm) polyps in the endoscopically nonvisualized colon.
Radiology 2007 244: 471-478 (DOI: 10.1148/radiol.2442060837); [Abstract] [Figures Only] [Full Text] [PDF]

Sang Won Lee, Seong Ho Park, Kyoung Won Kim, Eugene K. Choi, Yong Moon Shin, Pyo Nyun Kim, Kyoung Ho Lee, Eun Sil Yu, Shin Hwang, and Sung-Gyu Lee: Unenhanced CT for Assessment of Macrovesicular Hepatic Steatosis in Living Liver Donors: Comparison of Visual Grading with Liver Attenuation Index
Our results showed that the visual grading method was highly reproducible between readers and as accurate as the liver attenuation index method in the diagnosis of 30% or higher macrovesicular hepatic steatosis.
Radiology 2007 244: 479-485 (DOI: 10.1148/radiol.2442061177); [Abstract] [Figures Only] [Full Text] [PDF]

Massimo Bellomi, Giuseppe Petralia, Angelica Sonzogni, Maria Giulia Zampino, and Andrea Rocca: CT Perfusion for the Monitoring of Neoadjuvant Chemotherapy and Radiation Therapy in Rectal Carcinoma: Initial Experience
Perfusion CT may have an important clinical application in rectal cancer management; monitoring the response to therapy may lead clinicians to customize treatment to the response of the individual patient, and reliable prediction of the response may improve patient selection and avoid nonproductive, costly treatments.
Radiology 2007 244: 486-493 (DOI: 10.1148/radiol.2442061189); [Abstract] [Figures Only] [Full Text] [PDF]

Genitourinary Imaging:

Jingbo Zhang, Robert A. Lefkowitz, Nicole M. Ishill, Liang Wang, Chaya S. Moskowitz, Paul Russo, Halley Eisenberg, and Hedvig Hricak: Solid Renal Cortical Tumors: Differentiation with CT
Certain imaging features and the degree of enhancement on CT images are helpful in differentiating renal cortical tumor subtypes, despite some overlap.
Radiology 2007 244: 494-504 (DOI: 10.1148/radiol.2442060927); [Abstract] [Figures Only] [Full Text] [PDF] [Supplemental Figures and Tables]

Health Policy and Practice:

Debby van Helvoort-Postulart, Carmen D. Dirksen, Patricia J. Nelemans, Abraham A. Kroon, Alfons G. H. Kessels, Peter W. de Leeuw, G. Boudewijn C. Vasbinder, Jos M. A. van Engelshoven, and M. G. Myriam Hunink: Renal Artery Stenosis: Cost-effectiveness of Diagnosis and Treatment
Our study results show that diagnostic imaging testing for renal artery stenosis appears to be justified, even in a population of patients with hypertension and a relatively low prevalence of renal artery stenosis.
Radiology 2007 244: 505-513. Published online before print June 20 2007, 10.1148/radiol.2442060713 [Abstract] [Figures Only] [Full Text] [PDF] [Appendix E1]

Molecular Imaging:

Richard Schäfer, Rainer Kehlbach, Jakub Wiskirchen, Rüdiger Bantleon, Jörg Pintaske, Bernhard R. Brehm, Annika Gerber, Hartwig Wolburg, Claus D. Claussen, and Hinnak Northoff: Transferrin Receptor Upregulation: In Vitro Labeling of Rat Mesenchymal Stem Cells with Superparamagnetic Iron Oxide
Contrary to results reported in the current literature, our results reveal that superparamagnetic iron oxide or ultrasmall superparamagnetic iron oxide labeling without a transfection reagent does have a biologic impact on adult mesenchymal stem cells by upregulating transferrin receptor and suggest caution with use of this labeling procedure for clinical application.
Radiology 2007 244: 514-523. Published online before print June 11 2007, 10.1148/radiol.2442060599 [Abstract] [Figures Only] [Full Text] [PDF]

Musculoskeletal Imaging:

Pascale Bohy, Viviane de Maertelaer, Aymeric Roquigny, Caroline Keyzer, Denis Tack, and Pierre Alain Gevenois: Multidetector CT in Patients Suspected of Having Lumbar Disk Herniation: Comparison of Standard-Dose and Simulated Low-Dose Techniques
In multidetector CT of patients suspected of having disk herniation, the radiation dose could be reasonably reduced to 65% of the standard dose adapted for patient body mass index (BMI) (130 effective mAs if BMI <22 kg/m², 195 effective mAs if BMI $≥$ 22–<30 kg/m², and 260 effective mAs if BMI >30 kg/m²).
Radiology 2007 244: 524-531 (DOI: 10.1148/radiol.2442060606); [Abstract] [Figures Only] [Full Text] [PDF]

Neuroradiology:

Karsten Papke, Christiane K. Kuhl, Martin Fruth, Cornel Haupt, Martin Schlunz-Hendann, Dieter Sauner, Martin Fiebich, Alan Bani, and Friedhelm Brassel: Intracranial Aneurysms: Role of Multidetector CT Angiography in Diagnosis and Endovascular Therapy Planning
With 16–detector row CT angiography, intracranial aneurysms can be diagnosed with a performance that is comparable to that of digital subtraction angiography and can be assessed with respect to endovascular treatment options.
Radiology 2007 244: 532-540 (DOI: 10.1148/radiol.2442060394); [Abstract] [Figures Only] [Full Text] [PDF]

Erica C. S. Camargo, Karen L. Furie, Aneesh B. Singhal, Luca Roccatagliata, Mary E. Cunnane, Elkan F. Halpern, Gordon J. Harris, Wade S. Smith, Ramon G. Gonzalez, Walter J. Koroshetz, and Michael H. Lev: Acute Brain Infarct: Detection and Delineation with CT Angiographic Source Images versus Nonenhanced CT Scans
Our results show that, in this selected population, CT angiographic source images were both (a) more sensitive than nonenhanced CT scans in the early detection of irreversible middle cerebral artery infarction within 12 hours of symptom onset, without sacrifice of specificity, and (b) more accurate than nonenhanced CT scans in delineation of final infarct extent, as measured by using the Alberta Stroke Programme Early CT Score.
Radiology 2007 244: 541-548. Published online before print June 20 2007, 10.1148/radiol.2442061028 [Abstract] [Figures Only] [Full Text] [PDF]

Luis Martí-Bonmatí, Juan José Lull, Gracián García-Martí, Eduardo J. Aguilar, David Moratal-Pérez, Cecilio Poyatos, Montserrat Robles, and Julio Sanjuán: Chronic Auditory Hallucinations in Schizophrenic Patients: MR Analysis of the Coincidence between Functional and Morphologic Abnormalities
Coincidence analysis grouping functional MR abnormalities with focal brain density reductions in schizophrenic patients with chronic auditory hallucinations are largely depicted at the middle, superior temporal, and cingular gyri.
Radiology 2007 244: 549-556 (DOI: 10.1148/radiol.2442060727); [Abstract] [Figures Only] [Full Text] [PDF]

Nuclear Medicine:

Sandi A. Kwee, Jehoon P. Ko, Caroline S. Jiang, Michael R. Watters, and Marc N. Coel: Solitary Brain Lesions Enhancing at MR Imaging: Evaluation with Fluorine 18–Fluorocholine PET
As a surrogate method of measuring tissue choline metabolism, fluorocholine PET may aid in the differentiation of benign brain lesions, brain metastases, and high-grade gliomas.
Radiology 2007 244: 557-565. Published online before print June 20 2007, 10.1148/radiol.2442060898 [Abstract] [Figures Only] [Full Text] [PDF]

Klaus Strobel, Reinhard Dummer, Daniela B. Husarik, Marisol Pérez Lago, Thomas F. Hany, and Hans C. Steinert: High-Risk Melanoma: Accuracy of FDG PET/CT with Added CT Morphologic Information for Detection of Metastases
The results suggest that the added CT information improves the overall accuracy of integrated PET/CT for depiction of melanoma metastases not detected at PET.
Radiology 2007 244: 566-574 (DOI: 10.1148/radiol.2442061099); [Abstract] [Figures Only] [Full Text] [PDF]

Obstetric Imaging:

Jacques C. Jani, Mieke Cannie, Cleisson F. A. Peralta, Jan A. Deprest, Kypros H. Nicolaides, and Steven Dymarkowski: Lung Volumes in Fetuses with Congenital Diaphragmatic Hernia: Comparison of 3D US and MR Imaging Assessments
In fetuses with congenital diaphragmatic hernia, there is good correlation between lung volume measurements obtained with 3D US and those obtained with MR imaging for the contralateral lung but much poorer correlation for the ipsilateral lung.
Radiology 2007 244: 575-582 (DOI: 10.1148/radiol.2442061158); [Abstract] [Figures Only] [Full Text] [PDF]

Technical Developments:

Anand Kumar Singh, Dushyant V. Sahani, Christopher R. Kagay, Sanjeeva P. Kalva, Mukta C. Joshi, Nahel Elias, and Tatsuo Kawai: Semiautomated MIP Images Created Directly on 16-Section Multidetector CT Console for Evaluation of Living Renal Donors
Our study revealed that the maximum intensity projections from a predesigned protocol on the scanner console were much quicker to generate than similar images from three-dimensional workstations, and postprocessing demands (eg, the needs of renal donors) can be quickly fulfilled at the scanner console itself.
Radiology 2007 244: 583-590 (DOI: 10.1148/radiol.2442060909); [Abstract] [Figures Only] [Full Text] [PDF]

Thoracic Imaging:

Hakan Sahin, Kevin K. Brown, Douglas Curran-Everett, Valerie Hale, Carlyne D. Cool, Jason S. Vourlekis, and David A. Lynch: Chronic Hypersensitivity Pneumonitis: CT Features—Comparison with Pathologic Evidence of Fibrosis and Survival
The finding of a usual interstitial pneumonia pattern at CT occurred more often in patients with fibrotic hypersensitivity pneumonitis than in those with nonfibrotic hypersensitivity pneumonitis.
Radiology 2007 244: 591-598 (DOI: 10.1148/radiol.2442060640); [Abstract] [Figures Only] [Full Text] [PDF]

Vascular and Interventional Radiology:

Yao-Jun Zhang, Hui-Hong Liang, Min-Shan Chen, Rong-Ping Guo, Jin-Qing Li, Yun Zheng, Ya-Qi Zhang, and Wan Y. Lau: Hepatocellular Carcinoma Treated with Radiofrequency Ablation with or without Ethanol Injection: A Prospective Randomized Trial
Results of this prospective randomized study show that the combined use of radiofrequency ablation (RFA) and percutaneous ethanol injection was more effective than the use of RFA alone in terms of both local tumor recurrence and long-term survival for patients with hepatocellular carcinoma.
Radiology 2007 244: 599-607 (DOI: 10.1148/radiol.2442060826); [Abstract] [Figures Only] [Full Text] [PDF]

SIGNS IN IMAGING:

William M. Strub: The Arcuate Sign
The arcuate sign, which can be seen at standard anteroposterior radiography of the knee, is useful in diagnosing trauma to the posterolateral corner of the knee.
Radiology 2007 244: 620-621 (DOI: 10.1148/radiol.2442042160); [Figures Only] [Full Text] [PDF]

DIAGNOSIS PLEASE:

Yahya M. Berkmen and Benjamin A. Zalta: Case 126
Radiology 2007 244: 608-609 (DOI: 10.1148/radiol.2442040714); [Figures Only] [Full Text] [PDF]

Pamela T. Johnson, Karen M. Horton, and Elliot K. Fishman: Case 127
Radiology 2007 244: 610-612 (DOI: 10.1148/radiol.2442040998); [Figures Only] [Full Text] [PDF]

Mustafa Kemal Demir, Mahmut Beser, and Okan Akinci: Case 118: Proliferative Myositis
Proliferative myositis is a rare benign inflammatory myopathy characterized by infiltration with basophilic giant cells and proliferative fibroblasts.
Radiology 2007 244: 613-616 (DOI: 10.1148/radiol.2442041504); [Figures Only] [Full Text] [PDF]

J. Joost Kardux, H. Wouter van Es, and Benno J. W. M. Rensing: Case 119: Double-chambered Right Ventricle
The nature of the obstruction in patients with a double-chambered right ventricle is not well defined: Anomalous muscle bands that divide the right ventricle in either a low oblique or a high horizontal position have been described.
Radiology 2007 244: 617-619 (DOI: 10.1148/radiol.2442041242); [Figures Only] [Full Text] [PDF] [MPEG movie]

DEPARTMENTS:

: Abstracts of Current Literature
Radiology 2007 244: 627-628 (DOI: 10.1148/radiol.2442072526); [Full Text] [PDF]

: This Month in Radiology
Radiology 2007 244: 14-15 (DOI: 10.1148/radiol.2442200714); [PDF]

: Publication Information for Authors
Radiology 2007 244: [Full Text]